Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL10383732 | 0.95 | SMN1; SMN2 (0.51) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10385066 | 0.90 | ACE (0.49) | ACELMNASMN1; SMN2ALDH1A1ABCB11 | |
| SCHEMBL10521974 | 0.89 | ACE (0.44) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10521977 | 0.89 | ACE (0.44) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10383403 | 0.88 | ACE (0.58) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10520254 | 0.88 | ACE (0.45) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10520260 | 0.88 | ACE (0.45) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10520981 | 0.84 | ACE (0.50) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10520986 | 0.84 | ACE (0.50) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10935346 | 0.82 | CYP1A2 (0.50) | ACELMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | disclosed |