SCHEMBL10385181

SCHEMBL10385181

CCCCc1cc(CN)c(O)c(-c2cccc3[nH]nnc23)c1

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.31
ATP4A P20648 1/20 0.31
ATP4B P51164 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HTR1A P08908 1/20 0.31
ELANE P08246 1/20 0.30
CTSG P08311 1/20 0.30
PSMB5 P28074 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28973495 0.92 ELANE (0.34) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL28450073 0.89 LPL (0.36) ELANECTSG
SCHEMBL27396418 0.87 TLR8 (0.39) TLR8HTTHTR1AELANECTSG
SCHEMBL27494563 0.87 TLR8 (0.39) TLR8HTTHTR1AELANECTSG
SCHEMBL8446117 0.87 LPL (0.36) HPGDELANECTSGTP53
SCHEMBL29135489 0.83 GAA (0.34) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL29565084 0.81 ELANE (0.40) HPGDELANECTSG
SCHEMBL8149251 0.81 ELANE (0.40) HPGDELANECTSG
SCHEMBL7808234 0.81 ELANE (0.34) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL28309366 0.81 CNR1 (0.47) NPC1RAB9AHPGDMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4952664-A Process for producing weather-resistant polycarbonate with triazine-imide chain terminator MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-08-28 US disclosed