SCHEMBL28309366

SCHEMBL28309366

CCCCc1ccc(O)c(-c2cccc3[nH]nnc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
PSMB5 P28074 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
MAPK1 P28482 2/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALOX5 P09917 1/20 0.36
KAT8 Q9H7Z6 2/20 0.36
NFKB1 P19838 2/20 0.36
NFKB2 Q00653 2/20 0.36
RELA Q04206 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
LPL P06858 2/20 0.35
LIPG Q9Y5X9 2/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8101394 0.96 CNR1 (0.46) CNR1CNR2KAT8LPLLIPG
SCHEMBL2802977 0.95 CNR1 (0.44) CNR1CNR2KAT8LPLLIPG
SCHEMBL29199073 0.95 CNR1 (0.44) CNR1CNR2KAT8LPLLIPG
SCHEMBL30567518 0.93 CNR1 (0.56) CNR1CNR2MAPK1HPGDHTT
SCHEMBL28557327 0.91 NPC1 (0.41) PSMB5NPC1RAB9AMAPK1HPGD
SCHEMBL28713183 0.87 PPARA (0.43) KAT8
SCHEMBL28499025 0.86 BACE1 (0.41) CNR1CNR2NPC1RAB9AMAPK1
SCHEMBL28973495 0.83 ELANE (0.34) PSMB5NPC1RAB9AMAPK1HPGD
SCHEMBL27388475 0.82 ENPP2 (0.36) CNR1CNR2HPGDNPSR1GAA
SCHEMBL5420603 0.81 KDM4E (0.35) NPC1RAB9AMAPK1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107163493-B A kind of high durable exempts to spray imitative metal ABS composite material 中山市大亮彩塑胶新材料有限公司 2019-08-02 CN disclosed