Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385296 | 0.92 | CA1 (0.37) | CES2CES1CA2CA1 | |
| SCHEMBL2145650 | 0.83 | CES1 (0.33) | CES2CES1CA1 | |
| Acetic Acid SCHEMBL29714835 | 0.81 | CES1 (0.48) | CES2CES1CA2FABP3PPARG | |
| Acetic Acid SCHEMBL123724 | 0.81 | CES1 (0.48) | CES2CES1CA2FABP3PPARG | |
| Bicarbonate SCHEMBL28052430 | 0.81 | CES2 (0.48) | CES2CES1CA2FABP3PPARG | |
| Acetic Acid SCHEMBL630646 | 0.81 | CES1 (0.48) | CES2CES1CA2FABP3PPARG | |
| Oxalic Acid SCHEMBL10749415 | 0.81 | CES2 (0.48) | CES2CES1CA2FABP3PPARG | |
| Acetic Acid SCHEMBL3826722 | 0.81 | CES1 (0.48) | CES2CES1CA2FABP3PPARG | |
| Acetic Acid SCHEMBL4445253 | 0.81 | CES1 (0.48) | CES2CES1CA2FABP3PPARG | |
| SCHEMBL2784343 | 0.80 | CES2 (0.36) | CES2CES1CA2FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987005037-A1 | ROOM TEMPERATURE VULCANIZABLE ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 1987-08-27 | — | — | WO | claimed |
| US-4891402-A | Organic silicon-nitrogen compositions and their use as adhesion promoters in room temperature vulcanizable polydiorganosiloxane compositions | GENERAL ELECTRIC COMPANY (US) | 1990-01-02 | — | — | US | disclosed |
| WO-1987005037-A1 | ROOM TEMPERATURE VULCANIZABLE ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 1987-08-27 | — | — | WO | disclosed |