Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL630646 | 1.00 | CES1 (0.48) | CES1CES2CA2PPARGPPARD | |
| Acetic Acid SCHEMBL3826722 | 1.00 | CES1 (0.48) | CES1CES2CA2PPARGPPARD | |
| Acetic Acid SCHEMBL29714835 | 1.00 | CES1 (0.48) | CES1CES2CA2PPARGPPARD | |
| Acetic Acid SCHEMBL4445253 | 1.00 | CES1 (0.48) | CES1CES2CA2PPARGPPARD | |
| Oxalic Acid SCHEMBL10749415 | 0.91 | CES2 (0.48) | CES1CES2CA2PPARGPPARD | |
| Bicarbonate SCHEMBL28052430 | 0.91 | CES2 (0.48) | CES1CES2CA2PPARGPPARD | |
| Acetic Acid SCHEMBL37323 | 0.90 | CES1 (0.44) | CES1CES2CA2ALDH1A1CA1 | |
| Dodecanoate SCHEMBL18076263 | 0.90 | FABP3 (0.56) | CES1CES2GPR84FABP3CA1 | |
| SCHEMBL384850 | 0.89 | CES2 (0.43) | CES1CES2CA2PPARGPPARD | |
| SCHEMBL30353010 | 0.89 | CES2 (0.43) | CES1CES2CA2PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4180 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119463777-B | Long-acting mildew-proof joint beautifying agent and preparation method thereof | 广州白云科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119463147-B | Polyether ester polymer, preparation method thereof and application thereof in sealant | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-20260132307-A1 | A MATTING AGENT AND POLYURETHANE COATING COMPOSITIONS THEREWITH | GRACE GMBH (DE) | 2026-05-14 | — | — | US | claimed |
| US-20260015521-A1 | THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE | EASTMAN CHEMICAL COMPANY (US) | 2026-01-15 | — | — | US | claimed |
| EP-4144780-B1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO LTD (CN) | 2025-12-24 | — | — | EP | claimed |
| WO-2025234875-A1 | SILYL MODIFIED POLYMER ADHESIVE WITH IMPROVED OPEN TIME | STRONGBOND B.V. (NL) | 2025-11-13 | — | — | WO | claimed |
| WO-2025215142-A1 | KIT OF PARTS FOR PRODUCING A WALL AND FLOOR COATING | BRILLUX GMBH & CO. KG (DE) | 2025-10-16 | — | — | WO | claimed |
| US-12421417-B2 | Thermosetting coating composition with improved scratch resistance | EASTMAN CHEMICAL COMPANY (US) | 2025-09-23 | — | — | US | claimed |
| EP-4598976-A1 | A TWO-COMPONENT POLYURETHANE FOR POLYCARBONATE BONDING | ARKEMA FRANCE (FR) | 2025-08-13 | — | — | EP | claimed |
| US-12304991-B2 | Photochromic article | TRANSITIONS OPTICAL, LTD. (IE) | 2025-05-20 | — | — | US | claimed |
| EP-0972789-B1 | Aqueous silicone emulsion and base cloth for air bags treated therewith | SHINETSU CHEMICAL CO (JP) | 2006-04-12 | — | — | EP | claimed |
| EP-0982331-B1 | An improved process for the preparation of stable aqueous urethane dispersions | COUNCIL SCIENT IND RES (IN) | 2005-10-26 | — | — | EP | claimed |
| EP-0748658-B1 | A method for manufacturing a chemically adsorbed film and a chemical adsorbent solution for the method | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2002-09-18 | — | — | EP | claimed |
| EP-0643106-B1 | Organopolysiloxane compositions, their preparation and use, rubber articles coated with them | SHINETSU CHEMICAL CO (JP) | 1999-12-22 | — | — | EP | claimed |
| EP-0685460-B1 | PROCESS FOR PRODUCING HIGHER CYANOACETIC ESTER | MITSUBISHI RAYON CO (JP) | 1999-06-09 | — | — | EP | claimed |
| EP-0607900-B1 | Resin composition for artificial marble, bulk molding compound and sheet molding compound using the same, and process for preparing artificial marble using the same | HITACHI CHEMICAL CO LTD (JP) | 1999-04-14 | — | — | EP | claimed |
| EP-0507276-B1 | Conductive glass and manufacturing method thereof | NIPPON SHEET GLASS CO LTD (JP) | 1996-12-04 | — | — | EP | claimed |
| EP-0415594-B1 | Cationic electrodeposition paint composition | NISSAN MOTOR (JP) | 1994-10-26 | — | — | EP | claimed |
| EP-0398755-B1 | Composite paint film | NISSAN MOTOR (JP) | 1994-08-24 | — | — | EP | claimed |
| EP-0235049-B1 | TIN-BASED CATALYST MIXTURE FOR ROOM TEMPERATURE VULCANISABLE POLYSILOXANE COMPOSITIONS | RHONE-POULENC CHIMIE (FR) | 1990-07-11 | — | — | EP | claimed |