Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786121 | 0.81 | CA12 (0.38) | SPHK1USP2HTTMAPTCA12 | |
| SCHEMBL8508921 | 0.72 | SPHK1 (0.43) | SPHK1USP2HTTMAPTCA12 | |
| SCHEMBL5188138 | 0.71 | SPHK1 (0.46) | SPHK1USP2HTTMAPTCA12 | |
| SCHEMBL27887690 | 0.71 | SPHK1 (0.46) | SPHK1USP2HTTMAPTCA12 | |
| SCHEMBL11923393 | 0.71 | — | — | |
| SCHEMBL24175245 | 0.69 | THRB (0.44) | HTTHSD17B10MAPTCA12CA1 | |
| SCHEMBL10194014 | 0.69 | THRB (0.44) | HTTHSD17B10MAPTCA12CA1 | |
| SCHEMBL12348536 | 0.69 | THRB (0.44) | HTTHSD17B10MAPTCA12CA1 | |
| SCHEMBL20814113 | 0.68 | SPHK1 (0.40) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL2880158 | 0.68 | SPHK1 (0.51) | SPHK1USP2HTTHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918189-A | STABILIZE POLYMERS AGAINST THERMAL, OXIDATIVE, ACTINIC DEGRADATION | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0271446-A1 | Substituted hydroxylamines and compositions stabilized therewith | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | disclosed |
| US-4749733-A | POLYERMS, WAXES, OILS, FATS AGAINST THERMAL, OXIDATIVE, OR ACTINIC DEGRADATION | CIBA-GEIGY CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |