Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866412 | 1.00 | SPHK1 (0.51) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL2853926 | 1.00 | SPHK1 (0.51) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL19835199 | 0.79 | HTT (0.43) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL9658698 | 0.79 | HTT (0.43) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL19835254 | 0.79 | HTT (0.43) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL2900302 | 0.76 | MEN1 (0.52) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL5892442 | 0.76 | TSHR (0.40) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL13609383 | 0.75 | USP2 (0.49) | SPHK1USP2HTTLPAR5HSD17B10 | |
| SCHEMBL7351088 | 0.75 | MEN1 (0.50) | SPHK1USP2HTTMAPTMEN1 | |
| SCHEMBL10880822 | 0.75 | GGPS1 (0.56) | SPHK1MAPTGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151232-B1 | OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-04-12 | — | — | EP | disclosed |
| EP-1803434-B1 | Hair dye composition | KAO CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-7842101-B2 | Oxidative hair dye composition | KAO CORPORATION (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100154135-A1 | OXIDATIVE HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2151232-A1 | OXIDATIVE HAIR DYE COMPOSITION | Kao Corporation (JP) | 2010-02-10 | — | — | EP | disclosed |
| US-7507261-B2 | Hair dye composition | KAO CORPORATION (JP) | 2009-03-24 | — | — | US | disclosed |
| US-20090047231-A1 | AQUEOUS HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1905421-A1 | Hair dye composition | Kao Corporation (JP) | 2008-04-02 | — | — | EP | disclosed |
| US-20070157399-A1 | HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |
| EP-1803434-A1 | Hair dye composition | Kao Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100154135-A1 | OXIDATIVE HAIR DYE COMPOSITION | COXFA4, COXFA4L2, NDUFAB1 | SPHK1 4541/4885USP2 2564/4885HTT 943/4885 |
| US-20090047231-A1 | AQUEOUS HAIR COSMETIC COMPOSITION | POLR1C, CUTA, POLH | SPHK1 670/4885USP2 4171/4885HTT 285/4885 |
| US-20070157399-A1 | HAIR DYE COMPOSITION | SMOX, AOC3, TYR | SPHK1 647/4885USP2 3668/4885HTT 3857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.