Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089895 | 0.85 | AKR1B10 (0.62) | AKR1B10AKR1A1AKR1B1CYP2C9CDC25B | |
| SCHEMBL10352914 | 0.84 | AKR1B10 (0.80) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP1A2 | |
| SCHEMBL7113675 | 0.83 | AKR1B10 (0.65) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP2C9 | |
| SCHEMBL9575302 | 0.83 | AKR1B10 (0.61) | AKR1B10AKR1A1AKR1B1ALDH1A1HSD17B10 | |
| SCHEMBL10352844 | 0.83 | AKR1B10 (0.59) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP1A2 | |
| SCHEMBL9750457 | 0.83 | AKR1B10 (0.65) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP1A2 | |
| SCHEMBL10352845 | 0.83 | AKR1B10 (0.65) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10417267 | 0.82 | AKR1B10 (0.63) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP2C9 | |
| SCHEMBL10417266 | 0.82 | AKR1B10 (0.60) | AKR1B10AKR1A1AKR1B1ALDH1A1CYP1A2 | |
| SCHEMBL10415791 | 0.82 | AKR1B10 (0.60) | AKR1B10AKR1A1AKR1B1CDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962224-A | TREATMENT OR PREVENTION OF DIABETES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-09 | — | — | US | claimed |