Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331502 | 0.89 | DRD3 (0.44) | MEN1ALDH1A1KMT2ALMNADRD3 | |
| Hydrochloric Acid SCHEMBL9331483 | 0.88 | DRD3 (0.44) | MEN1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9759044 | 0.82 | LMNA (0.42) | ALDH1A1SMN1; SMN2LMNADRD3SLC6A3 | |
| SCHEMBL10385689 | 0.82 | ACHE (0.41) | MEN1ALDH1A1KMT2ACYP2C19CYP2C9 | |
| SCHEMBL9759043 | 0.75 | DRD3 (0.45) | MEN1ALDH1A1KMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL9759226 | 0.75 | DRD3 (0.45) | MEN1ALDH1A1KMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL9331534 | 0.74 | LMNA (0.46) | CYP2C19LMNADRD3SLC6A3PGR | |
| SCHEMBL9331364 | 0.73 | LMNA (0.41) | ALDH1A1SMN1; SMN2LMNADRD3SLC6A3 | |
| SCHEMBL9331494 | 0.72 | PTGS1 (0.47) | MEN1ALDH1A1KMT2ALMNADRD3 | |
| SCHEMBL9759590 | 0.72 | PTGS1 (0.47) | MEN1ALDH1A1KMT2ALMNADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912105-A | Derivatives of phenothiazine and the compositions which contain them | RHONE-POULENC SANTE (FR) | 1990-03-27 | — | — | US | disclosed |