SCHEMBL10386255

SCHEMBL10386255

CSc1c(C#N)c[c]cc1C#N

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
KDM4E B2RXH2 2/20 0.31
PTPN1 P18031 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15389443 0.75 TSHR (0.46) TSHRKDM4EPTPN1
SCHEMBL6965981 0.69 MEN1 (0.31) TSHR
SCHEMBL743155 0.67 TSHR (0.31) TSHR
SCHEMBL6199801 0.65
SCHEMBL28054995 0.65 TRPV4 (0.36)
SCHEMBL11254006 0.65 CSNK1A1 (0.32) KDM4E
SCHEMBL1926987 0.65
SCHEMBL457197 0.65 TSHR (0.41) TSHR
SCHEMBL27960343 0.64 CYP1A2 (0.36) TSHR
SCHEMBL6231963 0.64 TSHR (0.56) TSHRKDM4EPTPN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4978362-A Thermoplastic resin composition containing polyalkyleneoxy-substituted azo coloring agents having trifluoromethyl substituents MILLIKEN RESEARCH CORPORATION (US) 1990-12-18 US claimed
US-4751254-A COLORING POLURETHANES USING POLYALKOXYTRIFLUOROANILINE COMPOUNDS MILLIKEN RESEARCH CORPORATION (US) 1988-06-14 US claimed