Styrene

Styrene

SCHEMBL10386352

C=Cc1ccccc1.COC

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.78
TSHR P16473 1/20 0.78
TP53 P04637 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
TRPA1 O75762 3/20 0.44
HDAC8 Q9BY41 2/20 0.44
NFE2L2 Q16236 1/20 0.40
MAOB P27338 1/20 0.39
CA4 P22748 1/20 0.39
CYP2A6 P11509 1/20 0.39
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39
TUBB4B P68371 1/20 0.39
TUBB3 Q13509 1/20 0.39
TUBB2A Q13885 1/20 0.39
TUBB8 Q3ZCM7 1/20 0.39
TUBA3E Q6PEY2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL458690 0.90 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL7160606 0.88 ALDH1A1 (0.88) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL8336803 0.88 ALDH1A1 (0.88) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL6258482 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL11144289 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL369036 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL9776790 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL140 0.88
Styrene SCHEMBL1226310 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL10892600 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTP53TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920119-B Preparation method of aporphine alkaloid 中国药科大学 2023-05-23 CN claimed
CN-113004201-B Aporphine alkaloid derivative and preparation method and medical application thereof 中国药科大学 2022-08-05 CN claimed
CN-113004201-A Aporphine alkaloid derivative and preparation method and medical application thereof 中国药科大学 2021-06-22 CN claimed
CN-112920119-A Preparation method of aporphine alkaloid 中国药科大学 2021-06-08 CN claimed
CN-105829359-B Method for manufacturing the short chain macromolecular based on acrylate monomer 德莎欧洲股份公司 2018-03-16 CN claimed
CN-105264642-B Highly etch resistant polymer blocks in block copolymers for directed self assembly 布鲁尔科技公司 2018-03-09 CN claimed
CN-105829359-A Process for producing short-chain macromolecules based on acrylate monomers 德莎欧洲公司 2016-08-03 CN claimed
CN-105264642-A Highly etch resistant polymer blocks in block copolymers for directed self assembly BREWER SCIENCE INC 2016-01-20 CN claimed
CN-102337052-B Film-forming pigments and coating system including the same SILBERLINE MFG CO INC 2015-03-04 CN claimed
CN-103834063-A Method for coating ammonium polyphosphate with binary composite coating agent YUNNAN PHOSPHATE CHEM GROUP 2014-06-04 CN claimed
CN-103764112-A Personal care composition comprising butylated hydroxyanisole compound PROCTER & GAMBLE 2014-04-30 CN claimed
CN-103501756-A Composition for chemically modifying internal region of hair shaft PROCTER & GAMBLE 2014-01-08 CN claimed
CN-103391763-A Method for chemically modifying the internal region of a hair shaft PROCTER & GAMBLE 2013-11-13 CN claimed
CN-103172908-A Method for coating ammonium polyphosphate by using binary composite coating agent YUNNAN PHOSPHATE CHEM GROUP 2013-06-26 CN claimed
CN-102497850-A Method for chemically modifying the internal region of a hair shaft PROCTER & GAMBLE 2012-06-13 CN claimed
CN-101616738-B Macroporous polymers with larger pore sizes PUROLITE COMPANY 2011-11-23 CN claimed
CN-101605528-A Hair care composition PROCTER & GAMBLE (US) 2009-12-16 CN claimed
CN-100551944-C Polymer solid electrolyte NIPPON SODA CO (JP) 2009-10-21 CN claimed
CN-112920119-B Preparation method of aporphine alkaloid 中国药科大学 2023-05-23 CN disclosed
CN-86101133-A The superpolymer that contains isocyanate groups and derivative side group thereof with the preparation of emulsion copolymerization method 1986-09-03 CN disclosed