SCHEMBL1038644

SCHEMBL1038644

C=CC(=O)OC(C)CN(C)C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.44
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.34
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28946668 0.91 TSHR (0.38) TSHRALDH1A1HSD17B10HPGD
SCHEMBL28946684 0.90 TSHR (0.37) TSHRALDH1A1HSD17B10HPGD
SCHEMBL28946659 0.84 TSHR (0.36) TSHRHPGD
SCHEMBL28946652 0.82 TSHR (0.40) TSHRHPGD
SCHEMBL771037 0.82 TSHR (0.41) TSHRALDH1A1HSD17B10HPGDTP53
SCHEMBL28659892 0.81 SCN1A (0.42) TSHRALDH1A1HSD17B10HPGDTP53
SCHEMBL30648077 0.81 TSHR (0.41) TSHRALDH1A1HSD17B10HPGDTP53
SCHEMBL17522100 0.81 TSHR (0.41) TSHRALDH1A1HSD17B10HPGDTP53
Water SCHEMBL28238882 0.79 MBTD1 (0.41) TSHRALDH1A1HSD17B10HPGDTP53
SCHEMBL6275105 0.79 TSHR (0.50) TSHRALDH1A1HSD17B10HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4837196-A SUPPORT IMPREGNATED WITH STYRENE-ACRYLIC COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1989-06-06 US claimed
US-4734395-A CATIONIC SIZING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1988-03-29 US claimed
CN-103998549-B Can the adhesive article of hot unsticking and preparation and the method for this based article of use 3M创新有限公司 2016-10-12 CN disclosed
CN-103998549-A Debondable adhesive article and methods of making and using the same 3M INNOVATIVE PROPERTIES CO 2014-08-20 CN disclosed
CN-102458801-A Debondable adhesive article 3M INNOVATIVE PROPERTIES CO 2012-05-16 CN disclosed
EP-1270189-B1 Process for producing an ocular lens MENICON CO LTD (JP) 2011-01-26 EP disclosed
CN-1287046-C Method for producing paper and yield-improving agent SEIKO PMC CORP (JP) 2006-11-29 CN disclosed
CN-1643215-A Method for producing paper and yield-improving agent SEIKO PMC CORP (JP) 2005-07-20 CN disclosed
US-6790873-B2 Ocular lens and process for its production MENICON CO., LTD. (JP) 2004-09-14 US disclosed
US-20040054041-A1 NOVEL POLYMER BINDER SYSTEMS COMPRISING IONIC LIQUIDS DEGUSSA AG (DE) 2004-03-18 US disclosed
US-20030127758-A1 Ocular lens and process for its production MENICON CO., LTD. (JP) 2003-07-10 US disclosed
EP-1270189-A2 Ocular lens and process for its production Menicon Co., Ltd. (JP) 2003-01-02 EP disclosed
US-5133970-A WATER-SOLUBLE PRESSURE-SENSITIVE SKIN-ADHESIVE AND USE THEREOF ROHM GMBH CHEMISCHE FABRIK (DE) 1992-07-28 US disclosed
US-4837196-A SUPPORT IMPREGNATED WITH STYRENE-ACRYLIC COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1989-06-06 US disclosed
US-4734395-A CATIONIC SIZING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1988-03-29 US disclosed
US-3956571-A COATING WITH CATIONIC POLYMERS KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-05-11 US disclosed