Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038644 | 0.82 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28745471 | 0.81 | TSHR (0.45) | TSHRHPGDALDH1A1THRB | |
| SCHEMBL11320958 | 0.80 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6367761 | 0.76 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28734558 | 0.76 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL757462 | 0.76 | TSHR (0.42) | TSHRHPGDALDH1A1MAPK1 | |
| SCHEMBL561301 | 0.76 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| Trimethylammonium SCHEMBL27596408 | 0.75 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28946668 | 0.74 | TSHR (0.38) | TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL28946684 | 0.73 | TSHR (0.37) | TSHRHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916058-B2 | Fluorobetaine copolymer and fire fighting foam concentrates therefrom | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-12-23 | — | — | US | claimed |
| US-8916058-B2 | Fluorobetaine copolymer and fire fighting foam concentrates therefrom | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-12-23 | — | — | US | disclosed |
| US-8753615-B2 | Ethylene copolymer with PEG, cationic and anionic units, cosmetic composition including same and treatment method | L'OREAL (FR) | 2014-06-17 | — | — | US | disclosed |
| US-8753615-B2 | Ethylene copolymer with PEG, cationic and anionic units, cosmetic composition including same and treatment method | L'OREAL (FR) | 2014-06-17 | — | — | US | disclosed |
| US-20120070399-A1 | ETHYLENE COPOLYMER WITH PEG, CATIONIC AND ANIONIC UNITS, COSMETIC COMPOSITION INCLUDING SAME AND TREATMENT METHOD | L'OREAL (FR) | 2012-03-22 | — | — | US | disclosed |
| US-20120070399-A1 | ETHYLENE COPOLYMER WITH PEG, CATIONIC AND ANIONIC UNITS, COSMETIC COMPOSITION INCLUDING SAME AND TREATMENT METHOD | L'OREAL (FR) | 2012-03-22 | — | — | US | disclosed |
| EP-1676004-B1 | FIBROUS STRUCTURES EXHIBITING IMPROVED WET STRENGTH PROPERTIES | PROCTER & GAMBLE (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2010116063-A1 | ETHYLENE COPOLYMER WITH PEG, CATIONIC AND ANIONIC UNITS, COSMETIC COMPOSITION INCLUDING SAME AND TREATMENT METHOD | L'OREAL (FR) | 2010-10-14 | — | — | WO | disclosed |
| US-7799944-B2 | Process for the preparation of (meth)acrylate di-ammonium salts and their use as monomers for the synthesis of polymers | TAMINCO N.V. (BE) | 2010-09-21 | — | — | US | disclosed |
| US-20100168318-A1 | FLUOROBETAINE COPOLYMER AND FIRE FIGHTING FOAM CONCENTRATES THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2010-07-01 | — | — | US | disclosed |
| US-7217339-B2 | Fibrous structures exhibiting improved wet strength properties | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217339-B2 | Fibrous structures exhibiting improved wet strength properties | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-20070010591-A1 | Process for the preparation of (meth)acrylate di-ammonium salts and their use as monomers for the synthesis of polymers | TAMINCO NV (BE) | 2007-01-11 | — | — | US | disclosed |
| EP-1663948-A1 | PROCESS FOR THE PREPARATION OF (METH)ACRYLATE DI-AMMONIUM SALTS AND THEIR USE AS MONOMERS FOR THE SYNTHESIS OF POLYMERS | Taminco N.V. (BE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005023754-A1 | PROCESS FOR THE PREPARATION OF (METH)ACRYLATE DI-AMMONIUM SALTS AND THEIR USE AS MONOMERS FOR THE SYNTHESIS OF POLYMERS | TAMINCO N.V. (BE) | 2005-03-17 | — | — | WO | disclosed |
| EP-1512676-A1 | Process for the preparation of (meth)acrylate di-ammonium salts and their use as monomers for the synthesis of polymers | Taminco N.V. (BE) | 2005-03-09 | — | — | EP | disclosed |
| US-6841697-B2 | Process for preparing 2-(dimethylamino)-1-(dimethyl-aminomethyl) ethyl meth (acrylate) | ATOFINA (FR) | 2005-01-11 | — | — | US | disclosed |
| US-20020183543-A1 | Process for preparing 2-(dimethylamino)-1-(dimethyl-aminomethyl) ethyl meth (acrylate) | ATOFINA (FR) | 2002-12-05 | — | — | US | disclosed |
| US-6469204-B2 | P-XYLYLENE DICHLORIDE IS REACTED WITH DIMETHYLETHYL OR DIMETHYLISOPROPYLAMINE TO PRODUCE AN INTERMEDIATE, REACTING PRODUCT WITH (METH)ACRYLIC ACID, DIMETHYLAMINOETHYL ESTER OR (METH)ACRYLIC ACID, TETRAMETHYLDIAMINOISOPROPYL ESTER | ATOFINA (FR) | 2002-10-22 | — | — | US | disclosed |
| US-20020091284-A1 | NOVEL ACRYLATES COMPRISING SEVERAL QUATERNARY AMINO GROUPS IN THE ALCOHOL PART, THEIR PROCESS OF MANUFACTURE AND THE (CO) POLYMERS OBTAINED FROM THESE MONOMERS | ATOFINA (FR) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183543-A1 | Process for preparing 2-(dimethylamino)-1-(dimethyl-aminomethyl) ethyl meth (acrylate) | ADH1C, ADH1A, ADH5 | TSHR 575/4885HPGD 2327/4885ALDH1A1 20/4885 |
| US-20020091284-A1 | NOVEL ACRYLATES COMPRISING SEVERAL QUATERNARY AMINO GROUPS IN THE ALCOHOL PART, THEIR PROCESS OF MANUFACTURE AND THE (CO) POLYMERS OBTAINED FROM THESE MONOMERS | ADH1A, ADH1C, POLR2B | TSHR 2797/4885HPGD 1993/4885ALDH1A1 201/4885 |
| US-20120070399-A1 | ETHYLENE COPOLYMER WITH PEG, CATIONIC AND ANIONIC UNITS, COSMETIC COMPOSITION INCLUDING SAME AND TREATMENT METHOD | EGFR, ERCC1, ERCC5 | TSHR 2468/4885HPGD 1293/4885ALDH1A1 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.