Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 18/20 | 0.67 |
| ▸ | SLC5A1 | P13866 | 9/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17189182 | 0.90 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12285346 | 0.90 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL1038483 | 0.90 | SLC5A2 (0.61) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL3628095 | 0.90 | SLC5A2 (0.59) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12801854 | 0.90 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL9611976 | 0.90 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12285351 | 0.90 | SLC5A2 (0.61) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12285810 | 0.90 | SLC5A2 (0.59) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL15037575 | 0.90 | SLC5A2 (0.68) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18265370 | 0.90 | SLC5A2 (0.68) | SLC5A2SLC5A1ADRA2ASLC5A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308841-A2 | Phlorizin analogs as SGLT2 inhibitors | Lexicon Pharmaceuticals, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| EP-2089361-B1 | INHIBITORS OF SODIUM GLUCOSE CO-TRANSPORTER 2 AND METHODS OF THEIR USE | LEXICON PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | disclosed |