Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084475 | 0.98 | GAA (0.47) | GAATSHRCES2CYP4F2CYP4A11 | |
| SCHEMBL8941662 | 0.93 | TSHR (0.42) | GAATSHRCES2CYP4F2CYP4A11 | |
| SCHEMBL30737022 | 0.85 | TSHR (0.46) | GAATSHRCES2CYP4F2CYP4A11 | |
| 1-Pentanol SCHEMBL28223190 | 0.84 | MEN1 (0.47) | TSHRCES2ACHEHSD17B10MEN1 | |
| SCHEMBL260944 | 0.84 | — | — | |
| SCHEMBL7051236 | 0.83 | CES2 (0.61) | TSHRCES2MEN1THRBHTT | |
| SCHEMBL6463788 | 0.81 | TSHR (0.50) | GAATSHRCES2HSD17B10MGAM | |
| SCHEMBL11590882 | 0.81 | CES2 (0.39) | GAATSHRCES2HSD17B10MGAM | |
| SCHEMBL3732438 | 0.81 | TSHR (0.56) | GAATSHRCYP4F2CYP4A11ACHE | |
| SCHEMBL1036985 | 0.81 | TSHR (0.44) | GAATSHRCES2HSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118725012-A | Compound capable of inducing KRAS protein degradation and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| EP-1638936-B1 | 3-OXA-8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN INC (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-1638936-A1 | 3-OXA-8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | Allergan, Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108670-A1 | 3-OXA-8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-6734206-B1 | POTENT OCULAR HYPOTENSIVES THAT ARE PARTICULARLY SUITED FOR THE MANAGEMENT OF GLAUCOMA | ALLERGAN, INC. | 2004-05-11 | — | — | US | disclosed |