Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386745 | 0.87 | HTT (0.41) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL10386991 | 0.85 | HTT (0.40) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL10386884 | 0.85 | HTT (0.40) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL10386990 | 0.84 | POLB (0.40) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL10387154 | 0.83 | HSD17B1 (0.46) | HTTPKMPOLBCA2CA1 | |
| SCHEMBL1091841 | 0.80 | HTT (0.53) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL29645074 | 0.80 | HTT (0.53) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL1092424 | 0.76 | HTT (0.71) | HTTPKMPOLBALDH1A1LMNA | |
| SCHEMBL9285697 | 0.76 | XDH (0.46) | POLBCA2CA1CA9ALDH1A1 | |
| SCHEMBL12093774 | 0.76 | HTT (0.45) | HTTPKMPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162404-B1 | PROCESS FOR PREPARING 2-ALKYL-5-HALOACETYLBENZENESULFONAMIDE | SEITETSU KAGAKU CO., LTD. (JP) | 1988-08-24 | — | — | EP | claimed |
| EP-0162404-A2 | Process for preparing 2-alkyl-5-haloacetylbenzenesulfonamide | SEITETSU KAGAKU CO., LTD. (JP) | 1985-11-27 | — | — | EP | claimed |
| JP-61072744-A | — | — | None | — | — | JP | disclosed |
| JP-61251653-A | — | — | None | — | — | JP | disclosed |
| JP-58118557-A | — | — | None | — | — | JP | disclosed |
| US-4943655-A | INTERMEDIATE FOR AGRICULTURAL CHEMICALS AND PHARMACEUTICALS | SEITETSU KAGAKU CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4943655-A | INTERMEDIATE FOR AGRICULTURAL CHEMICALS AND PHARMACEUTICALS | SEITETSU KAGAKU CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4853158-A | CHEMICAL INTERMEDIATES; HYPOTENSIVE AGENTS | SEITETSU KAGAKU CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| US-4853158-A | CHEMICAL INTERMEDIATES; HYPOTENSIVE AGENTS | SEITETSU KAGAKU CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0162404-B1 | PROCESS FOR PREPARING 2-ALKYL-5-HALOACETYLBENZENESULFONAMIDE | SEITETSU KAGAKU CO., LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| JP-S61251653-A | CONTINUOUS PRODUCTION OF 5-ACETYL-2-ALKYLBENZENE SULFONAMIDE COMPOUND | SANKYO KAGAKU KK | 1986-11-08 | — | — | JP | disclosed |
| JP-S6172744-A | PREPARATION OF 2-ALKYL-5-HALOACETYLBENZENE SULFONAMIDE | SEITETSU KAGAKU CO LTD | 1986-04-14 | — | — | JP | disclosed |
| EP-0162404-A2 | Process for preparing 2-alkyl-5-haloacetylbenzenesulfonamide | SEITETSU KAGAKU CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| JP-S58118557-A | PREPARATION OF 5-ACETYL-2-ALKYLBENZENESULFONAMIDE | SEITETSU KAGAKU CO LTD | 1983-07-14 | — | — | JP | disclosed |