Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RGS12 | O14924 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388295 | 1.00 | GAA (0.54) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL10388117 | 0.82 | GAA (0.59) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL8422007 | 0.81 | GAA (0.58) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL10825727 | 0.79 | GAA (0.70) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL12125341 | 0.76 | HPGD (0.66) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL16295828 | 0.76 | HTT (0.67) | KDM4EHPGDLMNAPOLBALDH1A1 | |
| SCHEMBL16306922 | 0.76 | HTT (0.67) | KDM4EHPGDLMNAPOLBALDH1A1 | |
| SCHEMBL16295827 | 0.76 | HTT (0.67) | KDM4EHPGDLMNAPOLBALDH1A1 | |
| SCHEMBL10388646 | 0.76 | HPGD (0.59) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL11395073 | 0.75 | GAA (0.63) | GAATSHRKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918092-A | Leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1990-04-17 | — | — | US | disclosed |