Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295828 | 1.00 | HTT (0.67) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| SCHEMBL16306922 | 1.00 | HTT (0.67) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| 3-Prenyl-4-Hydroxyacetophenone SCHEMBL4120403 | 0.80 | HTT (1.00) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| SCHEMBL1092424 | 0.80 | HTT (0.71) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| SCHEMBL21960082 | 0.80 | HTT (0.57) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| SCHEMBL9574305 | 0.79 | PKM (1.00) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| SCHEMBL385574 | 0.77 | PKM (0.75) | HTTPKMPOLBHSD17B1ALDH1A1 | |
| SCHEMBL10388295 | 0.76 | GAA (0.54) | HTTPKMPOLBALDH1A1HPGD | |
| SCHEMBL10388294 | 0.76 | GAA (0.54) | HTTPKMPOLBALDH1A1HPGD | |
| SCHEMBL8845203 | 0.75 | PKM (0.72) | HTTPKMPOLBHSD17B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008078-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | Trustees of Boston College (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014201300-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2014-12-18 | — | — | WO | disclosed |