Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 5/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469942 | 1.00 | MAPK1 (0.43) | MAPK1ITGB3ITGA2BLTA4HPARP10 | |
| SCHEMBL10332951 | 1.00 | MAPK1 (0.43) | MAPK1ITGB3ITGA2BLTA4HPARP10 | |
| SCHEMBL11268633 | 0.89 | MAPK1 (0.46) | MAPK1ITGB3ITGA2BLTA4HPARP10 | |
| SCHEMBL11457731 | 0.89 | MAPK1 (0.46) | MAPK1ITGB3ITGA2BLTA4HPARP10 | |
| SCHEMBL10332953 | 0.88 | GAA (0.47) | MAPK1ITGB3ITGA2BLTA4HPARP10 | |
| SCHEMBL23258260 | 0.84 | MAPK1 (0.44) | MAPK1ITGB3ITGA2BLTA4HGAA | |
| SCHEMBL10425785 | 0.82 | LTA4H (0.38) | LTA4HALDH1A1HSD17B10HTTGRM8 | |
| SCHEMBL10333334 | 0.82 | LTA4H (0.38) | LTA4HALDH1A1HSD17B10HTTGRM8 | |
| SCHEMBL25601140 | 0.81 | MAPK1 (0.41) | MAPK1ITGB3ITGA2BLTA4HGAA | |
| SCHEMBL8311458 | 0.79 | MAPK1 (0.43) | MAPK1ITGB3ITGA2BLTA4HPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956358-A | ANTIBIOTICS, BACTERICIDES, CEPHALOSPORINS AND ISOCEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4891427-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |