Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425785 | 1.00 | LTA4H (0.38) | LTA4HKMT2ACYP1A2GRM8GRM6 | |
| SCHEMBL10779685 | 0.82 | TMPRSS15 (0.36) | LTA4HCYP1A2GRM8GRM6GRIN2D | |
| SCHEMBL10388482 | 0.82 | MAPK1 (0.43) | LTA4HGRM8GRM6GRM4ALDH1A1 | |
| SCHEMBL11469942 | 0.82 | MAPK1 (0.43) | LTA4HGRM8GRM6GRM4ALDH1A1 | |
| SCHEMBL10332951 | 0.82 | MAPK1 (0.43) | LTA4HGRM8GRM6GRM4ALDH1A1 | |
| SCHEMBL2266748 | 0.81 | GRM6 (0.46) | LTA4HKMT2ACYP1A2GRM8GRM6 | |
| SCHEMBL2266753 | 0.81 | GRM6 (0.46) | LTA4HKMT2ACYP1A2GRM8GRM6 | |
| SCHEMBL9329038 | 0.80 | LTA4H (0.38) | LTA4HKMT2ACYP1A2GRM8GRM6 | |
| SCHEMBL8126091 | 0.80 | LTA4H (0.38) | LTA4HKMT2ACYP1A2GRM8GRM6 | |
| SCHEMBL18172341 | 0.76 | KMT2A (0.50) | LTA4HKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4891427-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| US-4876251-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |