Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 8/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700383 | 0.88 | NPC1 (0.43) | NPC1GALR3S1PR4ALDH1A1MAPT | |
| SCHEMBL7700980 | 0.86 | NPC1 (0.45) | NPC1GALR3S1PR4ALDH1A1MAPT | |
| SCHEMBL8440532 | 0.82 | SRC (0.41) | SRCLCKTEKADKUSP2 | |
| SCHEMBL8442307 | 0.81 | ALDH1A1 (0.46) | NPC1GALR3S1PR4ALDH1A1MAPT | |
| SCHEMBL7699497 | 0.81 | IGF1R (0.43) | NPC1GALR3S1PR4ALDH1A1MAPT | |
| SCHEMBL8444992 | 0.81 | SRC (0.46) | SRCLCKTEKADKUSP2 | |
| SCHEMBL8441851 | 0.81 | DYRK3 (0.54) | RAB9ASRCLCKTEKADK | |
| SCHEMBL8442394 | 0.81 | SRC (0.46) | SRCLCKTEKADKUSP2 | |
| SCHEMBL8442195 | 0.78 | SRC (0.43) | SRCLCKTEKADKUSP2 | |
| SCHEMBL10388753 | 0.77 | SRC (0.41) | SRCLCKTEKADKUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968686-A | DECREASED CYTOTOXICITY; CYTOMEGALO AND HERPEX SIMPLEX VIRUSES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-11-06 | — | — | US | disclosed |