Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388752 | 0.82 | NPC1 (0.47) | SRCLCKTEKADKFLT3 | |
| SCHEMBL8444992 | 0.78 | SRC (0.46) | SRCLCKTEKADKFLT3 | |
| SCHEMBL8442394 | 0.78 | SRC (0.46) | SRCLCKTEKADKFLT3 | |
| SCHEMBL8441851 | 0.78 | DYRK3 (0.54) | SRCLCKTEKADKFLT3 | |
| SCHEMBL8991281 | 0.75 | ENPP1 (0.39) | SRCLCKTEKFLT3RET | |
| SCHEMBL7700383 | 0.75 | NPC1 (0.43) | SRCLCKTEKFLT3RET | |
| SCHEMBL8442195 | 0.75 | SRC (0.43) | SRCLCKTEKADKPIK3CD | |
| SCHEMBL10388753 | 0.72 | SRC (0.41) | SRCLCKTEKADKFLT3 | |
| SCHEMBL7700980 | 0.71 | NPC1 (0.45) | SRCLCKTEKADKFLT3 | |
| SCHEMBL7703236 | 0.71 | ADK (0.38) | SRCLCKTEKADKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36187-E | HERPES SIMPLEX VIRUS; HUMAN CYTOMEGALOVIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-04-06 | — | — | US | disclosed |
| US-4968686-A | DECREASED CYTOTOXICITY; CYTOMEGALO AND HERPEX SIMPLEX VIRUSES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-11-06 | — | — | US | disclosed |