Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777578 | 0.70 | PDE10A (0.50) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL666401 | 0.70 | TXNRD1 (0.49) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL10426653 | 0.69 | PDE10A (0.49) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL31122218 | 0.69 | PDE10A (0.49) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL4920165 | 0.69 | ALDH1A1 (0.50) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL558291 | 0.68 | SMN1; SMN2 (0.44) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL558555 | 0.68 | PSMB8 (0.44) | PDE10AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL2381198 | 0.68 | PSMB8 (0.56) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL4306213 | 0.68 | KDM4E (0.45) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 | |
| SCHEMBL15880740 | 0.68 | TDP1 (0.48) | TXNRD1TXNRD3TXNRD2PDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937669-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-02 | — | — | EP | claimed |
| WO-2007027959-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-08 | — | — | WO | claimed |
| US-20060280894-A1 | Metal complexes as light-absorbing compounds in the information layer of optical data carriers | LANXESS DEUTSCHLAND GMBH (DE) | 2006-12-14 | — | — | US | claimed |
| US-20060235210-A1 | Azo metal dyes and optical data carrier containing one such azo metal dye as a light absorbing compound in the information layer | LANXESS DEUTSCHLAND GMBH (DE) | 2006-10-19 | — | — | US | claimed |
| EP-1599548-A1 | METAL COMPLEXES AS LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS | LANXESS Deutschland GmbH (DE) | 2005-11-30 | — | — | EP | claimed |
| EP-1597321-A1 | AZO METAL DYES AND OPTICAL DATA CARRIER CONTAINING ONE SUCH AZO METAL DYE AS A LIGHT ABSORBING COMPOUND IN THE INFORMATION LAYER | LANXESS Deutschland GmbH (DE) | 2005-11-23 | — | — | EP | claimed |
| WO-2004072184-A1 | METAL COMPLEXES AS LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | claimed |
| WO-2004072185-A1 | AZO METAL DYES AND OPTICAL DATA CARRIER CONTAINING ONE SUCH AZO METAL DYE AS A LIGHT ABSORBING COMPOUND IN THE INFORMATION LAYER | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | claimed |
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | claimed |
| JP-1231031-A | — | — | None | — | — | JP | disclosed |
| JP-1200677-A | — | — | None | — | — | JP | disclosed |
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |
| US-7842688-B2 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2010-11-30 | — | — | US | disclosed |
| US-7799779-B2 | Substituted piperidines as renin inhibitors | NOVARTIS AG (CH) | 2010-09-21 | — | — | US | disclosed |
| US-4241166-A | UNSATURATED COMPOUND, BINDER, PHOTOINITIATOR; PRINTING PLATES, RESISTS, RELIEF IMAGES | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | disclosed |
| US-4208517-A | Caphalosporin compounds having at position-7 an α-etherified hydroxyiminoarylacetamido group | GLAXO OPERATIONS UK LIMITED (GB) | 1980-06-17 | — | — | US | disclosed |
| US-4144392-A | Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile | GLAXO LABORATORIES LIMITED (GB) | 1979-03-13 | — | — | US | disclosed |
| US-4103084-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-07-25 | — | — | US | disclosed |
| US-4007174-A | Cephalosporin compounds | GLAXO LABORATORIES LIMITED (EN) | 1977-02-08 | — | — | US | disclosed |
| US-3883504-A | Water-insoluble carbonylalkylene sulfonamido containing azo dyestuffs | HOECHST AG | 1975-05-13 | — | — | US | disclosed |