SCHEMBL10389477

SCHEMBL10389477

COc1ccccc1C12CCC(CC1)CC2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.49
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA14 Q9ULX7 1/20 0.44
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
HTR2C P28335 2/20 0.40
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12804463 0.82 CA1 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
SCHEMBL31027152 0.79 CNR2 (0.48) SIGMAR1CHRM2CHRM4CHRM5CHRM1
SCHEMBL647856 0.79 CNR2 (0.48) SIGMAR1CHRM2CHRM4CHRM5CHRM1
Hydrochloric Acid SCHEMBL1195892 0.77 CNR2 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
Bromide SCHEMBL1196185 0.77 CNR2 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
Bromide SCHEMBL1195236 0.77 CNR2 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
Hydrochloric Acid SCHEMBL1195889 0.77 CNR2 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
Bromide SCHEMBL1195238 0.77 CNR2 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
Bromide SCHEMBL1196187 0.77 CNR2 (0.46) SIGMAR1CHRM2CHRM4CHRM5CHRM1
SCHEMBL9326126 0.75 SIGMAR1 (0.55) SIGMAR1CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4895986-A CHEMICAL INTERMEDIATE COMMISSARIAT A L'ENERGIE (FR) 1990-01-23 US disclosed
US-4795579-A 2,2'-difluoro-4-alkoxy-4'-hydroxydiphenyls and their derivatives, their production process and their use in liquid crystal display devices COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1989-01-03 US disclosed