SCHEMBL647856

SCHEMBL647856

COc1ccccc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.48
FAAH O00519 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
RARA P10276 2/20 0.46
RARB P10826 2/20 0.46
RARG P13631 2/20 0.46
NR1I2 O75469 1/20 0.46
LMNA P02545 1/20 0.46
PGR P06401 1/20 0.46
HSPD1 P10809 1/20 0.46
GOT1 P17174 1/20 0.46
GLRA1 P23415 1/20 0.46
BLM P54132 1/20 0.46
HSPE1 P61604 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
EPHX2 P34913 1/20 0.46
SIGMAR1 Q99720 2/20 0.44
P2RX7 Q99572 1/20 0.44
HDAC11 Q96DB2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31027152 1.00 CNR2 (0.48) CNR2FAAHMEN1KMT2ARARA
Hydrochloric Acid SCHEMBL1195892 0.96 CNR2 (0.46) CNR2FAAHMEN1KMT2ARARA
Bromide SCHEMBL1196185 0.96 CNR2 (0.46) CNR2FAAHMEN1KMT2ARARA
Bromide SCHEMBL1196187 0.96 CNR2 (0.46) CNR2FAAHMEN1KMT2ARARA
Hydrochloric Acid SCHEMBL1195889 0.96 CNR2 (0.46) CNR2FAAHMEN1KMT2ARARA
Bromide SCHEMBL1195236 0.96 CNR2 (0.46) CNR2FAAHMEN1KMT2ARARA
Bromide SCHEMBL1195238 0.96 CNR2 (0.46) CNR2FAAHMEN1KMT2ARARA
SCHEMBL12804463 0.92 CA1 (0.46) CNR2FAAHMEN1KMT2ARARA
SCHEMBL13330401 0.86 RARA (0.42) CNR2FAAHMEN1KMT2ARARA
SCHEMBL3307015 0.84 CNR2 (0.51) CNR2FAAHMEN1KMT2ARARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4460726-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME Lightwave Logic, Inc. (US) 2024-11-13 EP claimed
WO-2023132934-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-07-13 WO claimed
US-20230212399-A1 Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same LIGHTWAVE LOGIC, INC. (US) 2023-07-06 US claimed
EP-3044216-B1 NOVEL AND SPECIFIC INHIBITORS OF CYTOCHROME P450 26 RETINOIC ACID HYDROXYLASE UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2022-02-23 EP claimed
CN-101193848-B Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid GALDERMA RESEARCH & DEVELOPMENT (FR) 2011-12-21 CN claimed
EP-1993986-B1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE FINORGA SAS (FR) 2010-07-14 EP claimed
US-20100010265-A1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE COMELY ALEXANDER CHRISTIAN 2010-01-14 US claimed
US-20090137841-A1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE FINORGA SAS (FR) 2009-05-28 US claimed
EP-1993986-A1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE FINORGA SAS (FR) 2008-11-26 EP claimed
CN-101193848-A Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid GALDERMA RES & DEV (FR) 2008-06-04 CN claimed
WO-2007063522-A1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE FINORGA SAS (FR) 2007-06-07 WO claimed
US-12565587-B2 Nonlinear optical chromophores having short-chain bridge structures, low optical loss materials containing the same, and methods for preparing the same LIGHTWAVE LOGIC, INC. (US) 2026-03-03 US disclosed
EP-4460726-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME Lightwave Logic, Inc. (US) 2024-11-13 EP disclosed
WO-2023132934-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-07-13 WO disclosed
US-20230212399-A1 Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same LIGHTWAVE LOGIC, INC. (US) 2023-07-06 US disclosed
WO-2008080993-A2 A METHOD FOR PREPARATION OF SUBSTITUTED ADAMANTYLARYLMAGNESIUM HALIDES KALVINSH IVARS (LV) 2008-07-10 WO disclosed
WO-2008080993-A2 A METHOD FOR PREPARATION OF SUBSTITUTED ADAMANTYLARYLMAGNESIUM HALIDES KALVINSH IVARS (LV) 2008-07-10 WO disclosed
CN-101193848-A Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid GALDERMA RES & DEV (FR) 2008-06-04 CN disclosed
US-20080091045-A1 Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid GALDERMA RESEARCH & DEVELOPMENT (FR) 2008-04-17 US disclosed
WO-2007063523-A1 INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE FINORGA SAS (FR) 2007-06-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565587-B2 Nonlinear optical chromophores having short-chain bridge structures, low optical loss materials containing the same, and methods for preparing the same CRY2, GJB2, CYBA CNR2 606/4885FAAH 2561/4885MEN1 2141/4885
US-20100010265-A1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE AMD1, CYP51A1, DDC CNR2 1626/4885FAAH 3210/4885MEN1 2401/4885
US-20080091045-A1 Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid CYP2B6, CYP2A6, CYP26B1 CNR2 2456/4885FAAH 189/4885MEN1 307/4885
US-20090137841-A1 PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE AMD1, CYP51A1, DDC CNR2 1626/4885FAAH 3210/4885MEN1 2401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.