Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389594 | 1.00 | HTT (0.56) | HTTTRPM8KMT2AMAPTMEN1 | |
| SCHEMBL600597 | 0.87 | HTT (0.70) | HTTTRPM8KMT2AMAPTMEN1 | |
| SCHEMBL154420 | 0.87 | HTT (0.70) | HTTTRPM8KMT2AMAPTMEN1 | |
| SCHEMBL10389557 | 0.86 | HTT (0.53) | HTTTRPM8KMT2AMAPTMEN1 | |
| SCHEMBL10389556 | 0.86 | HTT (0.53) | HTTTRPM8KMT2AMAPTMEN1 | |
| SCHEMBL17785153 | 0.83 | TRPM8 (0.57) | HTTTRPM8KMT2AMAPTTP53 | |
| SCHEMBL17785154 | 0.83 | TRPM8 (0.57) | HTTTRPM8KMT2AMAPTTP53 | |
| SCHEMBL17785161 | 0.81 | KMT2A (0.52) | HTTTRPM8KMT2AMAPTLMNA | |
| SCHEMBL17785159 | 0.81 | KMT2A (0.52) | HTTTRPM8KMT2AMAPTLMNA | |
| SCHEMBL27852393 | 0.81 | CA12 (0.54) | HTTTRPM8KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978523-A | P-hydroxycinnamides to remove pigment deposits in skin | KAO CORPORATION (JP) | 1990-12-18 | — | — | US | disclosed |