SCHEMBL600597

SCHEMBL600597

COc1ccc(/C=C/C(=O)OC2CCCCC2)cc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.70
TRPM8 Q7Z2W7 3/20 0.63
RAB9A P51151 1/20 0.58
F3 P13726 2/20 0.57
THRB P10828 1/20 0.55
ATM Q13315 1/20 0.55
GSK3B P49841 2/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC3 O15379 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
NR1H4 Q96RI1 1/20 0.50
LMNA P02545 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
BACE1 P56817 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154420 1.00 HTT (0.70) HTTTRPM8RAB9AF3THRB
SCHEMBL12608600 0.92 HTT (0.67) HTTTRPM8RAB9AF3THRB
SCHEMBL10389594 0.87 HTT (0.56) HTTTRPM8RAB9AF3MEN1
SCHEMBL10389595 0.87 HTT (0.56) HTTTRPM8RAB9AF3MEN1
SCHEMBL14679431 0.87 HTT (0.62) HTTRAB9AF3THRBATM
SCHEMBL17785153 0.87 TRPM8 (0.57) HTTTRPM8RAB9ATHRBMAPT
SCHEMBL17785154 0.87 TRPM8 (0.57) HTTTRPM8RAB9ATHRBMAPT
SCHEMBL18364671 0.87 HTT (0.61) HTTTRPM8RAB9AF3THRB
SCHEMBL8377642 0.86 HTT (0.58) HTTTRPM8RAB9AF3THRB
SCHEMBL17785161 0.85 KMT2A (0.52) HTTTRPM8RAB9AATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 853 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429699-B 5D stereoscopic embossment effect material and manufacturing process 石狮市冠鑫反光材料有限公司 2022-07-01 CN claimed
CN-113429699-A 5D stereoscopic embossment effect material and manufacturing process 石狮市冠鑫反光材料有限公司 2021-09-24 CN claimed
CN-112168722-A Sunscreen essence emulsion capable of effectively resisting ultraviolet injury and preparation method thereof 广州美莱洁化妆品开发有限公司 2021-01-05 CN claimed
CN-105407718-A Coated particles and compositions comprising the same VYOME BIOSCIENCES 2016-03-16 CN claimed
EP-1674095-B1 Phototherapy compositions OMJ IRELAND LTD (PR) 2014-08-20 EP claimed
CN-102356121-B Uv and light protective film HUHTAMAKI FORCHHEIM 2014-07-23 CN claimed
CN-101282708-B External preparation for skin containing a phosphorlated saccharide EZAKI GLICO CO 2013-03-20 CN claimed
EP-2379625-B1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM (DE) 2013-02-20 EP claimed
US-8168227-B2 Modified powder and cosmetic composition using the same SHISEIDO CO., LTD. (JP) 2012-05-01 US claimed
US-20110083765-A1 UV LIGHT AND PROTECTIVE FILM HUHTAMAKI FORCHHEIM, ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO (DE) 2011-04-14 US claimed
CN-1679475-B Hair cosmetic composition KAO CORP 2010-06-16 CN claimed
US-20070253989-A1 Modified Powder and Cosmetic Composition Using the Same SHISEIDO CO., LTD. (JP) 2007-11-01 US claimed
EP-1674095-A1 Phototherapy compositions OMJ Ireland Limited (PR) 2006-06-28 EP claimed
US-20060134031-A1 Phototherapy compositions and methods MALLINCKRODT ENTERPRISES LLC 2006-06-22 US claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-5554374-A Skin preparation using nanospheres COSMETICS DEVELOPMENT COMPANY LIMITED (GB) 1996-09-10 US claimed
US-12564549-B2 Cleanser composition SHISEIDO COMPANY, LTD. (JP) 2026-03-03 US disclosed
EP-4658626-A1 LAMINATED GLAZING COMPRISING A SILVER-BASED FUNCTIONAL COATING Saint-Gobain Glass France (FR) 2025-12-10 EP disclosed
EP-0211183-A2 Use of ubidecarenone(ubiquinone-10) as an antichromatotic agent Eisai Co., Ltd. (JP) 1987-02-25 EP disclosed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060134031-A1 Phototherapy compositions and methods VCL, TYR, TTPA HTT 3211/4885TRPM8 2852/4885RAB9A 4283/4885
US-12564549-B2 Cleanser composition LIPA, SGMS1, SGMS2 HTT 983/4885TRPM8 1974/4885RAB9A 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.