Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.78 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389654 | 0.87 | BRD4 (0.83) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3475782 | 0.87 | BRD4 (1.00) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30006979 | 0.87 | BRD4 (1.00) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389950 | 0.86 | BRD4 (0.81) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389880 | 0.86 | BRD4 (0.64) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389916 | 0.84 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389330 | 0.83 | BRD4 (0.74) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10390981 | 0.83 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10693221 | 0.83 | BRD4 (0.74) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389383 | 0.81 | BRD4 (0.72) | BRD4LIN28AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4654343-A | USEFUL AS ANXIOLYTIC OR ANTIEPILEPTIC AGENTS AS WELL AS SEDATIVE-HYPNOTIC AND SKELETAL MUSCLE RELAXANT AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |