Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 1.00 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006979 | 1.00 | BRD4 (1.00) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389654 | 0.91 | BRD4 (0.83) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389950 | 0.89 | BRD4 (0.81) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10390981 | 0.88 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10390958 | 0.87 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389916 | 0.87 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389391 | 0.87 | BRD4 (0.77) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4314112 | 0.86 | BRD4 (0.76) | BRD4LIN28AKDM4EHPGDHSD17B10 | |
| SCHEMBL10389330 | 0.85 | BRD4 (0.74) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10693221 | 0.85 | BRD4 (0.74) | BRD4LIN28AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035545-A1 | METHODS FOR MITIGATING CARDIAC AGING AND STRESS AND IMPROVIING CARDIAC FUNCTION | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (US) | 2024-02-15 | — | — | WO | claimed |
| WO-2010132286-A1 | ORALLY ADMINISTERED TABLET FORMULATION OF AN ANTIANXIOLYTIC COMPOUND | WYETH LLC (US) | 2010-11-18 | — | — | WO | claimed |
| EP-1885367-A2 | METHOD FOR THE TREATMENT OF NOISE PHOBIA IN COMPANION ANIMALS | Wyeth (US) | 2008-02-13 | — | — | EP | claimed |
| US-20060270677-A1 | Method for the treatment of noise phobia in companion animals | WYETH (US) | 2006-11-30 | — | — | US | claimed |
| WO-2006127574-A2 | METHOD FOR THE TREATMENT OF NOISE PHOBIA IN COMPANION ANIMALS | WYETH (US) | 2006-11-30 | — | — | WO | claimed |
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | claimed |
| US-4767765-A | ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-08-30 | — | — | US | claimed |
| WO-2024035545-A1 | METHODS FOR MITIGATING CARDIAC AGING AND STRESS AND IMPROVIING CARDIAC FUNCTION | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (US) | 2024-02-15 | — | — | WO | disclosed |
| US-20230059009-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-02-23 | — | — | US | disclosed |
| US-11246883-B2 | Microrna let-7 and transforming growth factor beta receptor III axis as target for cardiac injuries | ACADEMIA SINICA (TW) | 2022-02-15 | — | — | US | disclosed |
| CN-113181186-A | Application of 3-methyl- [1,2,4] triazolo [4,3-b ] pyridazine compound in preparation of medicines | 温州医科大学 | 2021-07-30 | — | — | CN | disclosed |
| WO-2021126779-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-24 | — | — | WO | disclosed |
| US-20190275070-A1 | MICRORNA LET-7 AND TRANSFORMING GROWTH FACTOR BETA RECEPTOR III AXIS AS TARGET FOR CARDIAC INJURIES | ACADEMIA SINICA (TW) | 2019-09-12 | — | — | US | disclosed |
| US-20060270677-A1 | Method for the treatment of noise phobia in companion animals | WYETH (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060270677-A1 | Method for the treatment of noise phobia in companion animals | WYETH (US) | 2006-11-30 | — | — | US | disclosed |
| WO-2006127574-A2 | METHOD FOR THE TREATMENT OF NOISE PHOBIA IN COMPANION ANIMALS | WYETH (US) | 2006-11-30 | — | — | WO | disclosed |
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4767765-A | ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0223974-A1 | N-Substituted-N-[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)-phenyl]alkanamides, carbamates and ureas | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
| US-4654343-A | USEFUL AS ANXIOLYTIC OR ANTIEPILEPTIC AGENTS AS WELL AS SEDATIVE-HYPNOTIC AND SKELETAL MUSCLE RELAXANT AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230059009-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | LIN28A, DDX21, BMI1 | BRD4 1177/4885LIN28A 1/4885KDM4E 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.