Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 1.00 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475782 | 1.00 | BRD4 (1.00) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389654 | 0.91 | BRD4 (0.83) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389950 | 0.89 | BRD4 (0.81) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10390981 | 0.88 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10390958 | 0.87 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389916 | 0.87 | BRD4 (0.78) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10389391 | 0.87 | BRD4 (0.77) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4314112 | 0.86 | BRD4 (0.76) | BRD4LIN28AKDM4EHPGDHSD17B10 | |
| SCHEMBL10389330 | 0.85 | BRD4 (0.74) | BRD4LIN28AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10693221 | 0.85 | BRD4 (0.74) | BRD4LIN28AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035545-A1 | METHODS FOR MITIGATING CARDIAC AGING AND STRESS AND IMPROVIING CARDIAC FUNCTION | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (US) | 2024-02-15 | — | — | WO | claimed |
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |
| WO-2024035545-A1 | METHODS FOR MITIGATING CARDIAC AGING AND STRESS AND IMPROVIING CARDIAC FUNCTION | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (US) | 2024-02-15 | — | — | WO | disclosed |
| EP-4077332-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2022-10-26 | — | — | EP | disclosed |