Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | USP10 | Q14694 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395335 | 0.86 | ALDH1A1 (0.72) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10395407 | 0.85 | KMT2A (0.81) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10395362 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL10394545 | 0.84 | KMT2A (0.80) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10395400 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10395379 | 0.81 | LMNA (0.68) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL4031948 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL10394634 | 0.79 | LMNA (0.65) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL1065694 | 0.78 | LMNA (0.57) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10394638 | 0.77 | KMT2A (1.00) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973599-A | ANTIINFLAMMATORY AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-11-27 | — | — | US | disclosed |