Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58994 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10395383 | 0.83 | POLB (0.46) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL10396008 | 0.82 | POLB (0.45) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10395379 | 0.79 | LMNA (0.68) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL4984369 | 0.77 | POLB (0.42) | ALDH1A1LMNAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL10394634 | 0.76 | LMNA (0.65) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10394638 | 0.74 | KMT2A (1.00) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL10395407 | 0.74 | KMT2A (0.81) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL10394545 | 0.73 | KMT2A (0.80) | ALDH1A1LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL5138758 | 0.72 | LMNA (0.62) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973599-A | ANTIINFLAMMATORY AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-11-27 | — | — | US | disclosed |