Succinimide

Succinimide

SCHEMBL10396113

NC(=O)C(N)=O.O=C1CCC(=O)N1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 9/20 0.65
DDB1 Q16531 4/20 0.36
NPC1 O15118 1/20 0.34
MAPK13 O15264 1/20 0.34
MAPK12 P53778 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
CA9 Q16790 1/20 0.34
TSHR P16473 1/20 0.32
ITGB3 P05106 1/20 0.32
ITGB1 P05556 1/20 0.32
ITGAV P06756 1/20 0.32
ITGA4 P13612 1/20 0.32
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30
IKZF3 Q9UKT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL28898484 0.91 CRBN (0.69) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL6036901 0.81 CRBN (0.73) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL434236 0.81 CRBN (0.73) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL6717091 0.81 CRBN (0.73) CRBNDDB1NPC1MAPK13MAPK12
Succinamide SCHEMBL6801732 0.81 CRBN (0.55) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL4602504 0.81
Succinimide SCHEMBL774 0.80
Succinimide SCHEMBL1466558 0.80
Succinimide SCHEMBL8361206 0.80 CRBN (1.00) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL1326078 0.80 CRBN (1.00) CRBNDDB1NPC1MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4927562-A NONDEGRADING TO ENGINE SEALS OF VITON\ TEXACO INC. (US) 1990-05-22 US disclosed
US-4501597-A Detergent fuel composition containing alkenylsuccinimide oxamides TEXACO INC. (US) 1985-02-26 US disclosed
US-4460381-A MONO-AND BIS-SUCCINIMIDE OF OXAMIDE TEXACO INC. (US) 1984-07-17 US disclosed