Succinamide

Succinamide

SCHEMBL6801732

NC(=O)CCC(N)=O.O=C1CCC(=O)N1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 5/20 0.55
DDB1 Q16531 2/20 0.41
ITGB3 P05106 1/20 0.33
ITGB1 P05556 1/20 0.33
ITGAV P06756 1/20 0.33
ITGA4 P13612 1/20 0.33
TSHR P16473 1/20 0.33
CAPN1 P07384 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CA9 Q16790 1/20 0.31
NPC1 O15118 1/20 0.31
MAPK13 O15264 1/20 0.31
MAPK12 P53778 1/20 0.31
MAPK11 Q15759 1/20 0.31
MAPK14 Q16539 1/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C19 P33261 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL28898484 0.84 CRBN (0.69) CRBNDDB1ITGB3ITGB1ITGAV
Succinimide SCHEMBL10396113 0.81 CRBN (0.65) CRBNDDB1ITGB3ITGB1ITGAV
Succinic Acid SCHEMBL436244 0.77 CRBN (0.58) CRBNITGB3ITGB1ITGAVITGA4
Succinimide SCHEMBL434236 0.75 CRBN (0.73) CRBNDDB1ITGB3ITGB1ITGAV
Succinimide SCHEMBL6717091 0.75 CRBN (0.73) CRBNDDB1ITGB3ITGB1ITGAV
Succinimide SCHEMBL6036901 0.75 CRBN (0.73) CRBNDDB1ITGB3ITGB1ITGAV
Succinimide SCHEMBL17844269 0.75 CRBN (0.55) CRBNDDB1ITGB3ITGB1ITGAV
Succinimide SCHEMBL16500285 0.75 CRBN (0.48) CRBNDDB1ITGB3ITGB1ITGAV
Succinimide SCHEMBL4602504 0.74
Succinimide SCHEMBL1466558 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110229216-B Compstatin peptides with improved pharmacokinetic properties 宾夕法尼亚州大学理事会 2023-06-16 CN disclosed
CN-115919996-A Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2023-04-07 CN disclosed
CN-107530396-B Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2022-08-26 CN disclosed
CN-113226211-A Compositions and methods for treating wounds CP医疗公司 2021-08-06 CN disclosed
CN-111032070-A Adiponectin peptidomimetics for the treatment of ocular diseases 雅利斯塔制药公司 2020-04-17 CN disclosed
CN-103987725-A Compstatin analogs with improved pharmacokinetic properties UNIV PENNSYLVANIA 2014-08-13 CN disclosed
CN-103930440-A Relaxin fusion polypeptides and uses thereof BAYER IP GMBH 2014-07-16 CN disclosed
CN-1693441-B Continuously variable transmission fluid INFINEUM INT LTD 2011-11-02 CN disclosed
CN-1997666-A Polyethylene glycol modified interferon compositions and methods of use thereof INTERMUNE INC (US) 2007-07-11 CN disclosed
CN-1938311-A Macrocyclic compounds as inhibitors of viral replication INTERMUNE INC (US) 2007-03-28 CN disclosed
WO-1998042808-A1 FUEL OIL COMPOSITIONS INFINEUM HOLDINGS BV (NL) 1998-10-01 WO disclosed
US-5460633-A Oil soluble polymer of an moldified mono-olefin EXXON CHEMICAL PATENTS INC. (US) 1995-10-24 US disclosed
EP-0641376-A1 FUEL OIL TREATMENT EXXON CHEMICAL PATENTS INC. (US) 1995-03-08 EP disclosed
WO-1993001259-A1 FUEL OIL TREATMENT EXXON CHEMICAL PATENTS INC. (US) 1993-01-21 WO disclosed
EP-0251419-B1 FUEL COMPOSITION AND ADDITIVE CONCENTRATES, AND THEIR USE IN INHIBITING ENGINE COKING ETHYL CORPORATION (US) 1989-05-31 EP disclosed
EP-0147240-B1 FUEL COMPOSITIONS AND ADDITIVE CONCENTRATES, AND THEIR USE IN INHIBITING ENGINE COKING ETHYL CORPORATION (US) 1989-04-05 EP disclosed
EP-0251419-A1 Fuel composition and additive concentrates, and their use in inhibiting engine coking ETHYL CORPORATION (US) 1988-01-07 EP disclosed
EP-0147240-A2 Fuel compositions and additive concentrates, and their use in inhibiting engine coking ETHYL CORPORATION (US) 1985-07-03 EP disclosed
US-4482357-A C,P/ CYLIDENE-1,2-PROPANEDIAMINE ETHYL CORPORATION (US) 1984-11-13 US disclosed
US-4482356-A ORGANIC NITRATE ETHYL CORPORATION (US) 1984-11-13 US disclosed