Succinimide

Succinimide

SCHEMBL28898484

NC(N)=O.O=C1CCC(=O)N1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 9/20 0.69
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
OR51E2 Q9H255 1/20 0.38
DDB1 Q16531 4/20 0.37
NPC1 O15118 1/20 0.36
MAPK13 O15264 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
CA9 Q16790 1/20 0.35
ITGB3 P05106 1/20 0.33
ITGB1 P05556 1/20 0.33
ITGAV P06756 1/20 0.33
ITGA4 P13612 1/20 0.33
TSHR P16473 1/20 0.33
IKZF3 Q9UKT9 1/20 0.31
MEN1 O00255 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL10396113 0.91 CRBN (0.65) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL6717091 0.84 CRBN (0.73) CRBNALDH1A1LMNADDB1NPC1
Succinimide SCHEMBL6036901 0.84 CRBN (0.73) CRBNALDH1A1LMNADDB1NPC1
Succinimide SCHEMBL434236 0.84 CRBN (0.73) CRBNALDH1A1LMNADDB1NPC1
Succinamide SCHEMBL6801732 0.84 CRBN (0.55) CRBNLMNADDB1NPC1MAPK13
Succinimide SCHEMBL4602504 0.83
Succinimide SCHEMBL774 0.83
Succinimide SCHEMBL1466558 0.83
Succinimide SCHEMBL8361206 0.83 CRBN (1.00) CRBNTDP1ALDH1A1LMNAOR51E2
Succinimide SCHEMBL1326078 0.83 CRBN (1.00) CRBNTDP1ALDH1A1LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108350490-B Substrates and methods for sequencing 生命技术公司 2022-06-21 CN disclosed
CN-108064253-B Polymer matrices formed from carboxy-functional acrylamides 生命技术公司 2020-09-15 CN disclosed