Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 11/20 | 0.67 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396923 | 0.89 | NR4A2 (0.62) | NR4A2CREBBPTP53SMN1; SMN2NPSR1 | |
| SCHEMBL4907150 | 0.89 | GPR84 (0.63) | NR4A2CREBBPGPR84TP53SMN1; SMN2 | |
| SCHEMBL4485057 | 0.86 | NR4A2 (0.68) | NR4A2CREBBPGPR84TP53NPSR1 | |
| SCHEMBL27365216 | 0.86 | NR4A2 (0.72) | NR4A2CREBBPGPR84TP53RAB9A | |
| SCHEMBL10397437 | 0.83 | NR4A2 (0.68) | NR4A2CREBBPGPR84TP53NPSR1 | |
| SCHEMBL2810907 | 0.82 | GPR84 (0.60) | NR4A2CREBBPGPR84TP53SMN1; SMN2 | |
| SCHEMBL25405774 | 0.81 | NR4A2 (1.00) | NR4A2CREBBPGPR84AXLMAP2K1 | |
| SCHEMBL31083673 | 0.81 | NR4A2 (1.00) | NR4A2CREBBPGPR84AXLMAP2K1 | |
| SCHEMBL4907106 | 0.80 | GPR84 (0.58) | NR4A2CREBBPGPR84TP53SMN1; SMN2 | |
| SCHEMBL4907100 | 0.79 | KDM4E (0.54) | NR4A2GPR84TP53SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950809-A | REACTING ARYL KETONE OR ALDEHYDE WITH PERACETIC ACID | RHONE-POULENC CHIMIE (FR) | 1990-08-21 | — | — | US | disclosed |