Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 9/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471952 | 0.81 | CYP3A4 (0.53) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL1792446 | 0.81 | CYP3A4 (0.53) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL1261641 | 0.80 | LMNA (0.59) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL10397110 | 0.80 | KDM4E (0.36) | LMNAACHEBCHEFAAHPTGS1 | |
| SCHEMBL10615391 | 0.76 | CYP3A4 (0.58) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL2475547 | 0.76 | CYP3A4 (0.58) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL16952898 | 0.74 | CYP3A4 (0.56) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL8780085 | 0.74 | CYP3A4 (0.45) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL11605832 | 0.74 | CYP3A4 (0.59) | CYP3A4LMNAACHEBCHEFAAH | |
| SCHEMBL6931924 | 0.74 | LMNA (0.44) | CYP3A4LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946921-A | POLYSILICATE CONTAINING HYDROXYPHENYL GROUP | TORAY SILICONE COMPANY LIMITED (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0342648-A2 | Alkali-soluble organopolysiloxane | TORAY SILICONE COMPANY, LIMITED (JP) | 1989-11-23 | — | — | EP | disclosed |