Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234964 | 0.80 | LMNA (0.50) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL111718 | 0.78 | TSHR (0.60) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL919843 | 0.77 | LMNA (0.50) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL24171452 | 0.76 | LMNA (0.48) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL13784555 | 0.76 | LMNA (0.48) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL8476326 | 0.76 | FFAR1 (0.53) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL19968620 | 0.76 | ESR1 (0.55) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL13799154 | 0.74 | TAAR1 (0.49) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL23502928 | 0.74 | LMNA (0.47) | LMNATSHRKDM4EESR1CYP3A4 | |
| SCHEMBL9506851 | 0.74 | LMNA (0.59) | LMNATSHRKDM4EESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | disclosed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | disclosed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | disclosed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |