Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396748 | 0.79 | KDM4E (0.39) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10396535 | 0.78 | KDM4E (0.39) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL28839383 | 0.77 | PARP1 (0.40) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1052126 | 0.76 | PARP1 (0.56) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11713701 | 0.76 | CDK2 (0.39) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10396143 | 0.75 | PKM (0.36) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL3257586 | 0.72 | PARP1 (0.54) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1756367 | 0.72 | PARP1 (0.63) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6848270 | 0.72 | PARP1 (0.63) | PARP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL21450709 | 0.72 | PARP1 (0.63) | PARP1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4919848-A | Process for the quenching of fluorescence, and new cationic naphthalene-peri-dicarboxylic acid imide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| US-4197111-A | 1,8-Naphthalimides and herbicide antidotes | STAUFFER CHEMICAL COMPANY (US) | 1980-04-08 | — | — | US | disclosed |