Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | STK10 | O94804 | 3/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.38 |
| ▸ | WEE1 | P30291 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396748 | 0.85 | KDM4E (0.39) | CDK2GSK3BGSK3ACHEK1WEE1 | |
| SCHEMBL10396535 | 0.84 | KDM4E (0.39) | CDK2GSK3BCHEK1WEE1CASP3 | |
| SCHEMBL10396745 | 0.76 | PARP1 (0.49) | GSK3BCASP3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10396143 | 0.75 | PKM (0.36) | GSK3BGSK3ACHEK1WEE1CASP3 | |
| SCHEMBL10396744 | 0.70 | ALDH1A1 (0.35) | GSK3BGSK3AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6550616 | 0.70 | PRMT1 (0.69) | CDK2STK10SLKCHEK1KDM4E | |
| SCHEMBL11713698 | 0.66 | KDR (0.39) | CDK2GSK3BGSK3AKDM4EALDH1A1 | |
| SCHEMBL29378366 | 0.65 | TOP1 (0.55) | CDK2GSK3BSTK10SLKCLK2 | |
| SCHEMBL384815 | 0.65 | TOP1 (0.55) | CDK2GSK3BSTK10SLKCLK2 | |
| SCHEMBL28114523 | 0.65 | MEN1 (0.50) | GSK3BCASP3KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |