Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963035 | 0.88 | OPRM1 (0.68) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL9371880 | 0.84 | OPRM1 (0.47) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL9466385 | 0.83 | OPRM1 (0.80) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9466353 | 0.83 | OPRM1 (0.80) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL10398382 | 0.83 | OPRM1 (0.71) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| Oxalic Acid SCHEMBL6045520 | 0.78 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9786448 | 0.76 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10460790 | 0.76 | OPRD1 (0.71) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10478955 | 0.75 | OPRM1 (0.61) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL3303683 | 0.74 | OPRM1 (0.80) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921864-A | 4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds | BOC, INC. (US) | 1990-05-01 | — | — | US | claimed |