SCHEMBL10397228

SCHEMBL10397228

COC(=O)C1=C(CCO)C2CCC1C2

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 11/20 0.44
SLC6A4 P31645 3/20 0.38
CYP4A11 Q02928 4/20 0.35
CYP4F2 P78329 3/20 0.35
ADRB3 P13945 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2286519 0.79 SLC6A3 (0.56) SLC6A3SLC6A4
SCHEMBL13517805 0.72 SLC6A3 (0.50) SLC6A3SLC6A4
SCHEMBL16229103 0.72 SLC6A3 (0.54) SLC6A3SLC6A4
SCHEMBL17318449 0.71 SLC6A3 (0.44) SLC6A3SLC6A4
SCHEMBL5918222 0.70 SLC6A3 (0.45) SLC6A3SLC6A4NPC1
SCHEMBL15586501 0.70 SLC6A3 (0.46) SLC6A3SLC6A4
SCHEMBL649338 0.70
SCHEMBL19051221 0.68 SLC6A3 (0.43) SLC6A3SLC6A4
SCHEMBL14072075 0.63 SLC6A3 (0.42) SLC6A3SLC6A4
SCHEMBL2328254 0.62 LMNA (0.47) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4855395-A Hydroxyethylnorbornene compounds and a process for their preparation EASTMAN KODAK COMPANY (US) 1989-08-08 US claimed
US-4895926-A Hydroxyethylnorbornene compounds and a process for their preparation EASTMAN KODAK COMPANY (US) 1990-01-23 US disclosed
US-4855395-A Hydroxyethylnorbornene compounds and a process for their preparation EASTMAN KODAK COMPANY (US) 1989-08-08 US disclosed
US-4789602-A Hydroxyethylnorbornene compounds and a process for their preparation EASTMAN KODAK COMPANY (US) 1988-12-06 US disclosed