SCHEMBL10397252

SCHEMBL10397252

[NH]C(=O)CCSCC[C]=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460293 0.79 LMNA (0.67) LMNAKMT2AHSD17B10TDP1ALDH1A1
SCHEMBL7708782 0.77
SCHEMBL300224 0.75
SCHEMBL11476145 0.73 LMNA (0.74) LMNAKMT2AHSD17B10TDP1ALDH1A1
SCHEMBL6277950 0.70
SCHEMBL9835411 0.69
SCHEMBL5660212 0.67
SCHEMBL3258854 0.67
SCHEMBL708978 0.66 TSHR (0.56) LMNAKMT2AHSD17B10TDP1
SCHEMBL10504612 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4978699-A Reaction product of hindered amine with primary amine or reactive hydrazide group and halogenated cyclic anhydride; for extrusion with polymers ATOCHEM NORTH AMERICA, INC. (US) 1990-12-18 US disclosed
EP-0366057-A2 Light stabilizing flame retardants ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1990-05-02 EP disclosed