SCHEMBL21861

SCHEMBL21861

O=C1OC(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 1.00
ALDH1A1 P00352 2/20 1.00
UCHL1 P09936 1/20 0.43
UCHL3 P15374 1/20 0.43
ECE1 P42892 1/20 0.43
MUS81 Q96NY9 1/20 0.43
AHR P35869 2/20 0.37
ALOX15 P16050 2/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CTSA P10619 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30354042 1.00 TSHR (1.00) TSHRALDH1A1UCHL1UCHL3ECE1
Water SCHEMBL28019026 0.97 TSHR (0.94) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL8995862 0.90 TSHR (0.82) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL15119603 0.85 TSHR (0.74) TSHRALDH1A1UCHL1UCHL3ECE1
Maleic Anhydride SCHEMBL27523758 0.84 ALDH1A1 (0.71) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL10397261 0.84 TSHR (0.71) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL854899 0.84 TSHR (0.71) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL8849220 0.84 TSHR (0.71) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL13578730 0.84 TSHR (0.72) TSHRALDH1A1UCHL1UCHL3ECE1
SCHEMBL15119611 0.83 TSHR (0.70) TSHRALDH1A1UCHL1UCHL3ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13384 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037845-A High-toughness epoxy resin packaging adhesive, preparation method and application 北京康美特科技股份有限公司 2026-05-15 CN claimed
CN-117821031-B Consolidated plugging material for oil-based drilling fluid and preparation method and application thereof 中国石油天然气集团有限公司 2026-05-12 CN claimed
US-20260015521-A1 THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE EASTMAN CHEMICAL COMPANY (US) 2026-01-15 US claimed
US-20250364645-A1 ELECTROCHEMICAL CELLS WITH FLAME RETARDANT MECHANISM AND METHODS OF PRODUCING THE SAME 24M TECHNOLOGIES, INC. (US) 2025-11-27 US claimed
US-20250313672-A1 Method for Preparing Lignocellulose Nanofibril and Composite Materials Reinforced Therewith ZHEJIANG UNIVERSITY (CN) 2025-10-09 US claimed
EP-4621114-A1 DEGRADABLE FILAMENT, PREPARATION METHOD THEREFOR, AND USE THEREOF Beijing Phabuilder Biotechnology Co., Ltd. (CN) 2025-09-24 EP claimed
US-12421417-B2 Thermosetting coating composition with improved scratch resistance EASTMAN CHEMICAL COMPANY (US) 2025-09-23 US claimed
US-12415892-B2 Polyimide film preparation method and application thereof INSTITUTE OF CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2025-09-16 US claimed
US-12385916-B2 Serum metabolic biomarkers and kit for detecting drug-resistant tuberculosis Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2025-08-12 US claimed
US-12381277-B2 Electrochemical cells with flame retardant mechanism and methods of producing the same 24M TECHNOLOGIES, INC. (US) 2025-08-05 US claimed
US-4066453-A PROCESS FOR THE PREPARATION OF PRINTING FORMS HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-03 US claimed
US-4013815-A FIRE RETARDANT UNSATURATED POLYESTERS HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-03-22 US claimed
US-3992480-A USED IN LAMINATED ARTICLES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-11-16 US claimed
US-3985661-A LUBRICANT-ABSORBING POWDER CARRIER SUMITOMO ELECTRIC INDUSTRIES, LTD. (JA) 1976-10-12 US claimed
US-3982938-A Photoconductive toners which include photoconductive pigment particles in a charge-transporting insulating binder FUJI PHOTO FILM CO., LTD. (JA) 1976-09-28 US claimed
US-3980735-A Hot melt adhesive composition TOYO SODA MANUFACTURING CO., LTD. (JA) 1976-09-14 US claimed
US-3980731-A Polyester compositions with carbonyl-containing compounds AKZONA INCORPORATED (US) 1976-09-14 US claimed
US-3948941-A NITRILE, FROM CARBOXYLIC ANHYDRIDES AND ISOCYANATES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-04-06 US claimed
US-3933700-A Modified polyurethane foams containing imide groups STANDARD OIL COMPANY (US) 1976-01-20 US claimed
US-3931354-A Reaction products of carboxyl terminated 1,2-polybutadiene with epoxides and aromatic bis(maleimides) TRW INC. (US) 1976-01-06 US claimed