Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640374 | 0.84 | TYR (0.50) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL3638975 | 0.83 | GABRA1 (0.53) | TYRTSHRNPSR1GABRA1GABRB2 | |
| SCHEMBL11349247 | 0.83 | TYR (0.49) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL11801194 | 0.81 | TYR (0.47) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL9191729 | 0.80 | TYR (0.50) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL11789246 | 0.80 | GSR (0.62) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL288102 | 0.80 | TYR (0.56) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL11651006 | 0.80 | TYR (0.56) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL10398728 | 0.79 | TYR (0.45) | TYRTSHRGAAHTTNPSR1 | |
| SCHEMBL10778517 | 0.79 | TYR (0.45) | TYRTSHRGAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937311-A | Heat resistant molding material | BAYER AKTIENGESELLSCHAFT, LEVERKUSEN, GERMANY, A CORP. OF GERMANY (DE) | 1990-06-26 | — | — | US | disclosed |
| EP-0340522-A2 | Aromatic polyesters and polyester carbonates with aralkyl phenyl end groups, their preparation and use | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| US-3991139-A | NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-11-09 | — | — | US | disclosed |