SCHEMBL3640374

SCHEMBL3640374

CCc1cc(C(C)c2ccccc2)c(O)c(C(C)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.50
HKDC1 Q2TB90 1/20 0.42
TSHR P16473 4/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
BRD4 O60885 2/20 0.41
TP53 P04637 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
IDO1 P14902 1/20 0.38
ESR1 P03372 1/20 0.38
PDCD1 Q15116 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249272 0.86 BRD4 (0.43) TYRTSHRGAAHTTNPSR1
SCHEMBL11349247 0.84 TYR (0.49) TYRHKDC1TSHRGAAHTT
SCHEMBL10397264 0.84 TYR (0.49) TYRHKDC1TSHRGAAHTT
SCHEMBL10778517 0.83 TYR (0.45) TYRHKDC1TSHRGAAHTT
SCHEMBL29668422 0.83 TYR (0.51) TYRHKDC1TSHRGAAHTT
SCHEMBL3640978 0.83 TYR (0.51) TYRHKDC1TSHRGAAHTT
SCHEMBL11801194 0.83 TYR (0.47) TYRHKDC1TSHRGAAHTT
SCHEMBL11789246 0.81 GSR (0.62) TYRTSHRGAAHTTNPSR1
SCHEMBL9191729 0.81 TYR (0.50) TYRHKDC1TSHRGAAHTT
SCHEMBL10776062 0.81 HTR2A (0.49) TYRTP53CYP3A4LMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162518-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2010-03-17 EP disclosed
WO-2009009293-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2009-01-15 WO disclosed
US-20090011961-A1 Lubricant compositions stabilized with styrenated phenolic antioxidant CROMPTON HOLDING CORPORATION 2009-01-08 US disclosed
EP-0117328-B1 LIQUID FUELS CONTAINING CORROSION INHIBITORS, AND INHIBITOR CONCENTRATES ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1987-04-29 EP disclosed
EP-0117328-A1 Liquid fuels containing corrosion inhibitors, and inhibitor concentrates ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1984-09-05 EP disclosed