Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.34 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397303 | 0.85 | MCL1 (0.40) | MCL1BCL2L1SELLSELPCSNK2A1 | |
| SCHEMBL10606135 | 0.82 | SELL (0.41) | MCL1SELLSELPCSNK2A1ALDH1A1 | |
| SCHEMBL3430274 | 0.82 | SELL (0.44) | MCL1BCL2L1SELLSELPAKR1C2 | |
| Water SCHEMBL10398683 | 0.81 | ALDH1A1 (0.40) | MCL1SELLSELPCSNK2A1ALDH1A1 | |
| SCHEMBL39596 | 0.80 | SELL (0.52) | MCL1BCL2L1SELLSELPAKR1C2 | |
| SCHEMBL10607191 | 0.79 | MCL1 (0.44) | MCL1SELLSELPCSNK2A1ALDH1A1 | |
| SCHEMBL1950367 | 0.79 | CYP1A2 (0.44) | AKR1C2AKR1C1ALDH1A1KDM4EALOX5 | |
| SCHEMBL10398467 | 0.78 | LMNA (0.43) | ALDH1A1KDM4EHSD17B10CA1CA2 | |
| Water SCHEMBL10398701 | 0.78 | MCL1 (0.43) | MCL1SELLSELPCSNK2A1ALDH1A1 | |
| SCHEMBL10398686 | 0.77 | KAT8 (0.46) | MCL1SELLSELPAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965395-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0224592-B1 | P-HYDROXYBENZOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0224592-A1 | p-HYDROXYBENZOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-06-10 | — | — | EP | disclosed |