Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396529 | 0.89 | NEK2 (0.46) | ALDH1A1MAPK1AKR1C3AKR1C2MAPT | |
| SCHEMBL10397096 | 0.85 | PDE4A (0.48) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10397852 | 0.83 | AKR1C3 (0.50) | HPGDALDH1A1KDM4ERAB9AHSD17B10 | |
| SCHEMBL14967415 | 0.80 | RXRB (0.43) | MYCALDH1A1KDM4EHSD17B10CYP2C9 | |
| SCHEMBL10417835 | 0.76 | AKR1C2 (0.51) | MYCHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10397855 | 0.76 | NEK2 (0.46) | ACHESMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL9810575 | 0.76 | ALDH1A1 (0.53) | HPGDSMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL2627845 | 0.76 | TRPA1 (0.48) | ALDH1A1HSD17B10CYP2C9CYP2C19KMT2A | |
| SCHEMBL13304652 | 0.75 | SLC6A2 (0.45) | CA1CA2ACHECYP3A4AKR1C3 | |
| SCHEMBL10397460 | 0.75 | PPARG (0.56) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |