Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL465908 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL9625167 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL4933917 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL992285 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL1832445 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL292514 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL3199266 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL7090995 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL4784041 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL2031974 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370982-A | Diphyllin derivatives, and preparation method and application thereof | UNIV NANKAI | 2015-02-25 | — | — | CN | claimed |
| CN-115466233-A | Synthetic method of brivaracetam intermediate (R) -4-propyl-dihydrofuran-2-ketone | 合肥立方制药股份有限公司 | 2022-12-13 | — | — | CN | disclosed |
| EP-1939204-B3 | FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2022-08-24 | — | — | EP | disclosed |
| CN-110522923-A | The matrix material of fructose and the co-modified dual-target triple negative breast cancer of RGD peptide | UNIV SICHUAN | 2019-12-03 | — | — | CN | disclosed |
| CN-106831721-B | Condensed heterocyclic compouds, preparation method, pharmaceutical composition and purposes | 上海璎黎药业有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106831722-B | Condensed heterocyclic compouds, preparation method, pharmaceutical composition and purposes | 上海璎黎药业有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-110016035-A | Support method is for related substance of cloth and the preparation method and application thereof | 天地恒一制药股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109956931-A | Tetrahydropyrrole compound, preparation method, pharmaceutical composition and purposes | 迈第康(上海)生物医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-106831883-B | A kind of compound and preparation method thereof for virus fluorescence label and living imaging | 清华大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-109153678-A | heterocyclic compounds as FGFR4 inhibitors | 杭州英创医药科技有限公司 | 2019-01-04 | — | — | CN | disclosed |
| EP-1344780-A1 | GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |
| CN-1036394-C | Process for preparing quinolone derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-11-12 | — | — | CN | disclosed |
| EP-0611749-B1 | Substituted amic acid derivatives useful for treatment of arteriosclerosis | BANYU PHARMA CO LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-5616803-A | EXHIBIT SQUALENE SYNTHASE-INHIBITORY ACTIVITIES; USEFUL IN TREATMENT AND PROPHYLAXIS OF HYPERCHOLESTEREMIA, HYPERLIPEMIA AND ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5606101-A | INTERMEDIATES FOR SQUALENE SYNTHASE INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5593943-A | Heteroaromatically condensed hydroxypyridonecarboxamides, their preparation and use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5488149-A | SQUALENE SYNTHASE INHIBITORS AS ANTICHOLESTEROL OR ANTILIPEMIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |
| US-5378679-A | PRE-AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| EP-0611749-A1 | Substituted amic acid derivatives useful for treatment of arteriosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |