Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373144 | 0.89 | MAPT (0.59) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL6269719 | 0.84 | MAPT (0.66) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL29200974 | 0.84 | MAPT (0.66) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL31317787 | 0.84 | MAPT (0.58) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL9804183 | 0.83 | HPGD (0.63) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL3083718 | 0.83 | HPGD (0.63) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL11351271 | 0.82 | MAPT (0.53) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL6269715 | 0.81 | MAPT (0.55) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL7101006 | 0.80 | MAPT (0.60) | MAPTRAB9AHPGDRECQLCA1 | |
| SCHEMBL12652047 | 0.80 | HPGD (0.59) | MAPTRAB9AHPGDRECQLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | disclosed |
| US-4925653-A | Sunscreen composition containing polyisobutylene and its use for the protection of human epidermis against ultraviolet radiations | L'OREAL (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4804531-A | Cosmetic screening composition containing a UV screen in combination with a polymer obtained by block polymerization in emulsion and its use for the protection of the human epidermis against ultraviolet radiations | L'OREAL (FR) | 1989-02-14 | — | — | US | disclosed |
| US-4668505-A | Sunscreen method containing polyisobutylene for the protection of human epidermis against ultraviolet radiations | L'OREAL (FR) | 1987-05-26 | — | — | US | disclosed |